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Landscape

Noise-Induced Hearing Loss

Noise-Induced Hearing Loss has 18 tracked records across 8 named organizations, including 2 strong-evidence records and 5 active programs. Records with caveats and trial-derived candidates remain visible for deeper review.

Open filtered programs
18
Pipeline Records
strong evidence + caveats + candidates
2
Strong Evidence
16 checked records with caveats
5
Active Programs
currently active
0
Marketed / Approved
commercial or approved
8
Organizations
companies, sponsors, and institutions
Competitive Density
28/100
organization breadth + program volume
Pipeline Velocity
23/100
active and late-stage share
Evidence Coverage
11/100
share strong evidence
Completion Signal
11/100
late-stage, approved, or marketed
Attrition Rate
28/100
share discontinued
Concentration
61/100
top-organization share

Programs by Stage

Preclinical2 · 11%
Phase 12 · 11%
Phase 1/23 · 17%
Phase 27 · 39%
Phase 32 · 11%
Not applicable2 · 11%

Trial / Program Status

Active5 · 28%
Completed7 · 39%
Discontinued5 · 28%
Unknown1 · 6%

Modality Breakdown

Small Molecule12 · 67%
Regenerative Medicine4 · 22%
Biologic1 · 6%
Drug Delivery1 · 6%

Program Types

Therapeutic18 · 100%

Top Organizations

Institution-led study11 · 61%
Boehringer Ingelheim1 · 6%
Edison Pharmaceuticals Inc.1 · 6%
Frequency Therapeutics1 · 6%
Otologic Pharmaceutics1 · 6%
Otonomy1 · 6%
Sound Pharmaceuticals1 · 6%
Truway Health, Inc.1 · 6%

Population Tags

adult18 · 100%
noise-induced15 · 83%
tinnitus7 · 39%
age-related3 · 17%
healthy-volunteer2 · 11%
otoprotection2 · 11%
repurposed-drug2 · 11%
sensorineural2 · 11%
study-level2 · 11%
sudden2 · 11%

Checked Records With Caveats

16 records
FX-322 by Frequency Therapeutics
Company: Frequency Therapeutics · Phase 2 · Discontinued
Regenerative MedicinePhase 2Discontinued96% confidence
NHPN-1010
Company: Otologic Pharmaceutics · Phase 1 · Completed
Small MoleculePhase 1Completed89% confidence
OTO-6XX by Otonomy
Company: Otonomy · Preclinical · Discontinued
Regenerative MedicinePreclinicalDiscontinued84% confidence
National Taiwan University NAC Noise-Induced Hearing Loss StudyStatus caveat
Sponsor / Institution: Institution-led study · Phase 2 · Completed
Small MoleculePhase 2Completed88% confidence
University of Michigan Soundbites micronutrient NIHL prevention studyStatus caveat
Sponsor / Institution: Institution-led study · Phase 2 · Completed
Small MoleculePhase 2Completed86% confidence
Gabapentin tinnitus study clusterStatus caveat
Sponsor / Institution: Institution-led study · Phase 2 · Completed
Small MoleculePhase 2Completed86% confidence
Zinc gluconate tinnitus and noise-induced hearing-loss studyStatus caveat
Sponsor / Institution: Institution-led study · Not applicable · Completed
Small MoleculeNot applicableCompleted86% confidence
Antioxidant prevention study for noise-induced hearing loss and tinnitusStatus caveat
Sponsor / Institution: Institution-led study · Not applicable · Unknown
Small MoleculeNot applicableUnknown84% confidence
Southern Illinois D-Methionine Noise-Induced Hearing Loss StudyStatus caveat
Sponsor / Institution: Institution-led study · Phase 3 · Discontinued
Small MoleculePhase 3Discontinued84% confidence
EPI-743 by Edison Pharmaceuticals for noise-induced hearing lossStatus caveat
Company: Edison Pharmaceuticals Inc. · Phase 2 · Completed
Small MoleculePhase 2Completed84% confidence
Washington University/Gateway zonisamide acute noise-induced hearing loss studiesStatus caveat
Sponsor / Institution: Institution-led study · Phase 2 · Discontinued
Small MoleculePhase 2Discontinued84% confidence
Colorado LOOT clemastine plus engineered sound CAPD studyStatus caveat
Sponsor / Institution: Institution-led study · Phase 1/2 · Active
Small MoleculePhase 1/2Active82% confidence
Wayne State etanercept blast/noise-induced tinnitus studyStatus caveat
Sponsor / Institution: Institution-led study · Phase 2 · Active
BiologicPhase 2Active82% confidence
SNUH dexamethasone/hyaluronic-acid intratympanic delivery studyStatus caveat
Sponsor / Institution: Institution-led study · Phase 1/2 · Completed
Drug DeliveryPhase 1/2Completed76% confidence
Zonisamide and Methylprednisolone Noise-Induced Hearing Loss Prevention StudyStatus caveat
Sponsor / Institution: Institution-led study · Phase 1/2 · Discontinued
Small MoleculePhase 1/2Discontinued72% confidence
Truway Health HEAR-RESTORE exploratory inner-ear regenerative studyStatus caveat
Company: Truway Health, Inc. · Phase 1 · Active
Regenerative MedicinePhase 1Active68% confidence