Therapeutics
Details checkedClinical trial listing onlyHistorical/discontinuedCheckedregistry

Zonisamide and Methylprednisolone Noise-Induced Hearing Loss Prevention Study

Also known as: Zonisamide, Methylprednisolone, Noise-induced hearing loss prevention study

Institution-led study

Primary source
Sponsor / Institution
Institution-led study
Program Type
Therapeutic
Modality
Small Molecule
Stage
Phase 1/2
Status
Discontinued
Target Gene
Route / Mode
Oral
Confidence
72%
Status Confidence
Status needs checking
Evidence Strength
Needs more support
Last Reviewed
2026-06-10
Geography
United States
Population
adult, noise-induced, study-level
Trial IDs
1
Mechanism

Withdrawn academic Phase 1/2 prevention study comparing oral zonisamide, methylprednisolone, and no medication around temporary noise exposure.

Indications
Notes

ClinicalTrials.gov verifies a withdrawn Washington University Phase 1/2 prevention study. The record was generated from one intervention arm, but the source trial included both zonisamide and methylprednisolone comparators; it should be read as a study-level historical record, not a standalone zonisamide program.

Evidence & Sources
1 structured sources
clinicaltrials
Supports: canonicalName, aliases, company, allCompanies, isIndustrySponsored, programType, modality, mechanism...
IDs: NCT02049073
Open
Key Events
Clinical Trials (1)
Data Checks
institution-led-studyregistry-verified-studydiscontinued-registry-studygeneric-drug-studymerged-generated-intervention-armsnot-commercial-pipeline-program
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