Therapeutics
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Ospedale San Raffaele Tirzepatide Study in Wolfram Syndrome Type 1

Also known as: Tirzepatide, Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1, NCT05659368

Institution-led study

Primary source
Sponsor / Institution
Institution-led study
Program Type
Therapeutic
Modality
Small Molecule
Stage
Phase 2
Status
Unknown
Target Gene
Route / Mode
Subcutaneous injection
Confidence
82%
Status Confidence
Status needs checking
Evidence Strength
Needs more support
Last Reviewed
2026-06-10
Geography
Italy
Population
genetic, syndromic, pediatric, adult
Trial IDs
1
Mechanism

Phase 2 institution-led study of once-weekly subcutaneous tirzepatide monotherapy in Wolfram syndrome type 1, a rare syndromic disease with hearing-loss relevance.

Indications
Notes

Verified as a real Wolfram syndrome type 1 tirzepatide study. It is included as a hearing-adjacent syndromic record rather than a dedicated hearing-loss therapeutic program; the registry status is Unknown and estimated completion has passed.

Evidence & Sources
1 structured sources
clinicaltrials
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IDs: NCT05659368
Open
Key Events
Clinical Trials (1)
Data Checks
institution-led-studyregistry-only-evidenceregistry-status-unknownhearing-adjacent-syndromic-record
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