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São Paulo dexamethasone/hyaluronic acid cochlear-implant study

Also known as: Hearing preservation using dexamethasone and hyaluronic acid, Hybrid L24 Implant, NCT01588925

Institution-led study

Primary source

Sponsor / Institution

Institution-led study

Program Type

Therapeutic

Modality

Drug Delivery

Stage

Phase 2

Status

Completed

Target Gene

—

Route / Mode

Topical round-window dexamethasone and electrode-array hyaluronic acid during cochlear implantation

Confidence

82%

Status Confidence

Status needs checking

Evidence Strength

Needs more support

Last Reviewed

2026-06-10

Geography

Brazil

Population

adult, cochlear-implant, sensorineural, profound, hearing-preservation

Trial IDs

Mechanism

Completed Phase 2 cochlear-implantation study testing topical dexamethasone with or without hyaluronic acid around Hybrid L24 implantation to preserve residual hearing.

Indications

Hearing Loss Sensorineural Hearing Loss

Notes

Verified as an institution-led cochlear-implant hearing-preservation study. This is not a standalone steroid product; it is a perioperative drug-delivery/hearing-preservation protocol in cochlear implantation.

Evidence & Sources

1 structured sources

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IDs: NCT01588925

Open

Key Events

2011-11-01

São Paulo cochlear-implant hearing-preservation study started

2014-01-01

Registry lists study completion date

Clinical Trials (1)